A study on correlation between deficiency of vitamin D and knee osteoathritis among patients attending a tertiary care hospital in Andhra Pradesh

Authors

  • Komala Rao Department of Orthopaedics, Great Eastern Medical School and Hospital, Ragolu, Srikakulam, Andhra Pradesh, India
  • V. Ramesh Department of Orthopaedics, Great Eastern Medical School and Hospital, Ragolu, Srikakulam, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20203961

Keywords:

Osteoarthritis, Knee joint pain, 25-OH vitamin D, Andhra Pradesh

Abstract

Background: The prevalence of vitamin D deficiency is the burning topic worldwide. Vitamin D deficiency is a under diagnosed medical condition since a significant proportion of the population in many countries and regions around the world have low serum 25-hydroxy (OH) vitamin D levels. The aim of this study was to investigate the association between serum vitamin D deficiency and knee osteoarthritis (OA).

Methods: The study population consists of 200 patients divided into two groups, group 1 and group 2. Group 1 with 100 subjects with no clinical features of knee osteoarthritis served as controls and group 2 consists of 100 patients of patients diagnosed with knee osteoarthritis. Serum 25-OH vitamin D was measured in all the participants by the enzyme-linked fluorescence assay (ELFA) method and concentrations <20 ng/ml was considered as deficient.

Results: In group 1, 47% were male and 53% were female whereas in group 2, 41% were male and 59% were female. In group 1, only 8% are vitamin D deficiency whereas in group 2, 61% have vitamin D deficiency. There was a significant association between serum vitamin D and staging of knee OA.

Conclusions: The present study findings showed a significant association between serum 25-OH vitamin D deficiency and in patients with knee OA.

Author Biography

Komala Rao, Department of Orthopaedics, Great Eastern Medical School and Hospital, Ragolu, Srikakulam, Andhra Pradesh, India

Assistant professor

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Published

2020-10-22

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Original Research Articles